MT-1 (Melanotan 1) vs MT-2 (Melanotan 2)
At 10mg, the only strength both sell by the single box, MT-1 is the cheaper per mg: $0.742 per mg against $0.783 (MT110, MT10). MT-1 is offered in 1 strength, MT-2 in 1. Neither is on the shelf today.
Prices revised · USD per box of ten · freight included to US addresses from $1,000 of goods · COA per batch · research use only · New to us? What can be checked before you pay
What differs between MT-1 and MT-2
Melanotan 1 is a linear thirteen-residue analogue of alpha-MSH with norleucine at 4 and D-phenylalanine at 7; Melanotan 2 is a seven-residue analogue closed into a ring by a lactam bond between aspartate and lysine side chains. Masses 1646.9 and 1024.2. Both carry one tryptophan. A buyer comparing them per milligram should note the very different molecular weights: a milligram of MT-2 is about 1.6 times as many molecules as a milligram of MT-1.
| Detail | MT-1 | MT-2 |
|---|---|---|
| Best price per mg | $0.742 per mg (MT110) | $0.783 per mg (MT10) |
| Price per box sold singly | $74.20 | $78.32 |
| Strengths offered | 1: 10mg | 1: 10mg |
| Highest price per mg | $0.742 per mg (MT110) | $0.783 per mg (MT10) |
| On the shelf today | No, made to order | No, made to order |
| Range | Cosmetic & Skin | Cosmetic & Skin |
| Also called | afamelanotide | Melanotan II and MT-II |
| Form | Lyophilised powder | Lyophilised powder |
| Molecular weight | 1,646.9 g/mol | 1,024.2 g/mol |
| Formula | C78 |
C50 |
| CAS number | 75921-69-6 | 121062-08-6 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Each line’s own page: MT-1 (Melanotan 1) and MT-2 (Melanotan 2). Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold; stock as this page was opened.
| Strength | MT-1 | MT-2 |
|---|---|---|
| 10mg | $0.742 per mg (lower) (MT110, made to order) | $0.783 per mg (MT10, made to order) |
Every strength of both
Compared elsewhere
Questions
What is the difference between MT-1 and MT-2?
Melanotan 1 is a linear thirteen-residue analogue of alpha-MSH with norleucine at 4 and D-phenylalanine at 7; Melanotan 2 is a seven-residue analogue closed into a ring by a lactam bond between aspartate and lysine side chains. Masses 1646.9 and 1024.2.
Which run of residues is common to MT-1 and MT-2?
His-D-Phe-Arg-Trp, four in a row: at 6 to 9 in MT-1’s linear chain and 3 to 6 in MT-2’s ring. Both also carry a norleucine and a lysine, placed differently. In MT-2 the lysine follows the tryptophan and its side chain is bonded to the aspartate before the histidine, which closes the ring; MT-1 has a glutamate before the histidine and runs on through Gly-Lys-Pro-Val. Each opens with an acetylated residue, serine in MT-1 and norleucine in MT-2, and each ends in an amide.
Which is cheaper per mg, MT-1 or MT-2?
At 10mg, the only strength both sell by the single box, MT-1 is the cheaper per mg: $0.742 per mg against $0.783 (MT110, MT10).
What are the molecular weights of MT-1 and MT-2?
MT-1’s calculated average mass is 1,646.9 g/mol and MT-2’s 1,024.2 g/mol, 622.7 apart; in electrospray the ions come at m/z 824.4 and 550.0 (2+ and 3+) for MT-1 against 1025.2 and 513.1 (1+ and 2+) for MT-2. On each certificate the measured mass is matched to the line’s calculated average mass, within about one unit, as how to read a peptide COA sets out. PT-141, at 1025.2, sits within one unit of MT-2; at high resolution their [M+H]+ ions are m/z 1024.548 for MT-2 and 1025.532 for PT-141.
Are MT-1 and MT-2 made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, matched to the calculated figure on each sheet. The retest date is on the batch record. What differs is each molecule’s own chemistry, described on its compound page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.