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SNAP-8 wholesale

SNAP-8, also called acetyl octapeptide-3. Bulk peptide powder in 10-vial kits, for sale in the USA and abroad: price and cost per mg

About SNAP-8

Synthetic N-acetylated, C-amidated octapeptide whose sequence is taken from the N-terminal domain of SNAP-25 (acetyl octapeptide-3), Ac-EEMQRRAD-NH2. 2 vial strengths, 10mg to 100mg, from $56.54 per box of ten, in US dollars. Made to order in about four weeks or special order (50-box minimum), as marked.

CAS number 868844-74-0
Formula C41H70N16O16S
Molecular weight 1075.17 g/mol
Residues 8
Purity ≥ 98.0 %(RP-HPLC, 220 nm)
Form Lyophilised powder
Storage −20 °C, dark and dry
Box 10 sealed vials

SNAP-8 price per box, per vial and per mg

Code Strength Per box Per vial Per mg Stock Order
NP810 10mg x 10 vials $56.54 $5.65 $0.565 per mg Made to order, 4 weeks
NP8100 100mg x 10 vials $436.00 $43.60 Lowest, 50 boxes $0.436 per mg Special order, 50-box minimum

Ships from the USA: to US addresses at our risk until delivered (DAP), freight included from $1,000 of goods; to Canada and most other countries through the desk · on-shelf lines leave in 1 to 2 business days, then 1 to 3 business days in US transit · COA per batch · proforma in USD, paid by card, Wise, e-Transfer (Canada), Bitcoin or USDT · prices revised

Stock key

In stock
on the shelf, leaves in 1 to 2 business days once payment clears
Low stock
on the shelf and running low; leaves in 1 to 2 business days
Ships in 1 week
on its way in
Ships in 2 weeks
on order
Made to order, 4 weeks
made for the order, about four weeks
Special order, 50-box minimum
brought in on a 50-box minimum rather than held in stock; the desk confirms the date before you pay

Prices are in US dollars per sealed box. Per unit is the box price over the milligrams, millilitres or units in the box.

SNAP-8 in brief

SNAP-8 comes in 2 strengths, 10mg and 100mg per vial, each a sealed box of ten: NP810 at $56.54 by the single box, NP8100 at $436.00 in 50-box lots.

Nothing is on the shelf today. NP810 is made to order, about four weeks, in any quantity. NP8100 is special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.

What SNAP-8 is

SNAP-8, acetyl octapeptide-3, is a synthetic eight-residue amide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, average mass 1075.2, an extension by two residues of the hexapeptide acetyl hexapeptide-3. It is an acidic, hydrophilic chain with an acetylated N-terminus.

Its one methionine, at 3, oxidises to the sulfoxide, 16 heavier, and its glutamine, at 4, deamidates to glutamate, about 1 heavier, so those two forms are the related substances to expect. The two residues it adds to the hexapeptide, alanine and aspartate, end the chain, the aspartate as the C-terminal amide. It dissolves instantly.

SNAP-8 beside GHK-Cu and Glutathione

SNAP-8 works out at $0.565 per mg at 10mg (NP810), its lowest by the single box. Its neighbours: GHK-Cu at $0.052 per mg at 100mg (CU100), 401.9 g/mol, glycyl-histidyl-lysine bound to copper(II), with no methionine in it; Glutathione at $0.00359 per mg at 1500mg (GTT), 307.3 g/mol, a tripeptide whose one sulfur is a free thiol that pairs into GSSG, where SNAP-8’s is a methionine.

Reading a SNAP-8 certificate of analysis (COA)

Identity by mass. Average mass 1075.2 (C41H70N16O16S). In electrospray the protonated ions come near m/z 1076.2 (singly charged), m/z 538.6 (doubly charged); on our certificates the measured mass is matched to the calculated average mass, within about one unit.

  • Oxidation: 1 methionine, which oxidises to the sulfoxide. The sulfoxide makes the chain 16 heavier.
  • Deamidation: 1 glutamine. The deamidated form is 0.984 heavier and a little more negatively charged, inside the tolerance of the average-mass line; telling it apart takes a high-resolution mass, which the certificate does not carry.
  • N-terminus: capped with an acetyl group, so there is no free N-terminal amine.
  • Charge: near neutral pH about -1, acidic.

Worked out from what the sheet holds for this line; the batch certificate is the record. How to read one, and verify a batch number.

Buy SNAP-8 in bulk

SNAP-8 is sold in bulk by the sealed box of ten vials, and every account starts at list price. Two discounts can lower it, the size of one order (from $5,000 of goods) or the account’s tier (from lifetime paid spend), and the better one applies, never both. Priced below on NP810, 10mg x 10 vials, the best-priced strength.

Discount Earned by Off goods NP810 per box Per mg
List Every account, any order none $56.54 $0.565
Order size $5,000 of goods in one order 5% $53.71 $0.537
Order size $10,000 of goods in one order 10% $50.89 $0.509
Order size $20,000 of goods in one order 15% $48.06 $0.481
Order size $50,000 of goods in one order 20% $45.23 $0.452
Silver tier $5,000 lifetime paid spend 3% $54.84 $0.548
Gold tier $15,000 lifetime paid spend 6% $53.15 $0.531
Platinum tier $50,000 lifetime paid spend 10% $50.89 $0.509
Diamond tier $100,000 lifetime paid spend 15% $48.06 $0.481

Thresholds in USD on goods, before freight; the discount is worked out at checkout and shown on the proforma.

Specification

The limits this compound is supplied to.

Purity ≥ 98.0 % (RP-HPLC, 220 nm, area normalisation)
Identity ESI-MS against a calculated average mass of 1075.2
Any single related substance ≤ 1.0 %
Water ≤ 8.0 % (Karl Fischer)
Acetate ≤ 15.0 % (ion chromatography), as the acetate salt
Residual solvents Acetonitrile ≤ 410 ppm; TFA ≤ 1.0 %
Net content Label claim ± 5 %
Closure 2 mL glass vial, bromobutyl stopper, aluminium flip-off seal
Storage −20 °C, dark and dry; brief ambient transit tolerated
Shelf life 24 months from manufacture; retest date on the batch record

Order SNAP-8

One box of NP810, 10mg x 10 vials, $56.54 a box. Every strength.

Questions about SNAP-8

Is acetyl octapeptide-3 the same as SNAP-8?

Yes. Acetyl octapeptide-3 and SNAP-8 are names for the same thing. Acetyl octapeptide-3 describes the line: an N-acetylated, C-amidated octapeptide from the N-terminal domain of SNAP-25. The certificate and the vial label carry SNAP-8, which is the name the batch is released under.

What are SNAP-8’s sequence, formula, molecular weight and CAS number?

Ac-EEMQRRAD-NH2, eight residues, acetylated at the N-terminus and amidated at the C-terminus: C41H70N16O16S, molecular weight (average mass) 1,075.2, CAS 868844-74-0.

Why does SNAP-8 carry a negative charge?

Its acidic residues, two glutamates, at 1 and 2, plus the aspartate at 8, outnumber its two arginines, at 5 and 6, and neither end adds a charge, the N-terminus being acetylated and the C-terminus an amide. That leaves it at -1 overall, with five of its eight residues charged.

What do SNAP-8’s last two residues add to the six-residue chain it extends?

Alanine at 7 and aspartate at 8, C7H10N2O4, which weighs about 186.2 of the chain’s 1,075.2, so the six-residue amide it extends, Ac-EEMQRR-NH2, comes to about 889.0, as C34H60N14O12S. SNAP-8’s sixteen nitrogens sit eight in the backbone, one in each residue, six in the two arginines’ side chains, one in the glutamine’s and one in the C-terminal amide, while the formula’s single S belongs to methionine 3.

How much does SNAP-8 cost?

From $56.54 a sealed box of 10 vials, which works out at $0.565 per mg at its best-priced size. NP8100 is special order, 50 boxes at least, at $436.00 a box. To a US address, freight is included from $1,000 of goods; below that it is the carrier’s rate for the carton or a flat $35.00, and to another country the desk quotes it; either way the figure is on the proforma before you pay. Every strength and its price per vial is in this page’s price table.

Which SNAP-8 size is cheapest per mg?

Of the sizes sold by the single box, NP810, 10mg x 10 vials, at $0.565 per mg. Sold only by special order, NP8100 is lower still, at $0.436 per mg, with a 50-box minimum.

Can I buy a single vial of SNAP-8?

No. One sealed box of ten vials is the smallest quantity of a regular line; for SNAP-8 that is NP810, 10mg x 10 vials, at $56.54. A first order must reach $100 of goods, so NP810 alone takes two boxes ($113.08) or one box beside other lines. NP8100 is special order and takes a minimum of 50 boxes. A box is sealed at fill with its batch number on it, and splitting one would break the link between the vials and their certificate.

Which SNAP-8 strengths are in stock today?

None today. NP810 is made to order, about four weeks, in any quantity. NP8100 is special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.

How is SNAP-8 stored?

At minus 20 degrees Celsius, dark and dry. Lyophilised powder tolerates a short spell at ambient temperature in transit, which is why boxes ship without ice. Storage and handling.

What is in a box of SNAP-8?

Ten sealed vials of one strength, each labelled with the product code, the strength and the batch number; the trade also calls a box a 10-vial kit. SNAP-8 is supplied as a powder in a sealed glass vial and in no other presentation. Boxes are not split.

Is a certificate of analysis (COA) provided for SNAP-8?

Yes. For SNAP-8 the batch certificate reports its purity, net content and identity by mass spectrometry. The other lines on this page are the specification it is made to, and the desk answers for them on a particular batch. The certificate is sent with the shipment, and again on request, and any batch number can be verified on the certificate page.

Is this for human use?

No. Everything here is supplied for laboratory research only, to trade accounts, and is not for human or animal consumption. The research-use page sets out who can buy and what is not sold.

Special order