Liraglutide vs Tirzepatide
Strength for strength, Tirzepatide costs less per mg at the two strengths both sell by the single box: at 10mg $0.442 per mg against $0.603 (TR10, LIR10), at 30mg $0.330 per mg against $0.523 (TR30, LIR30). Liraglutide is offered in 3 strengths (5mg to 30mg), Tirzepatide in 12 (5mg to 120mg); Tirzepatide has 3 on the shelf today, Liraglutide none (made to order, about four weeks).
Prices revised · USD per box of ten · freight included to US addresses from $1,000 of goods · COA per batch · research use only · New to us? What can be checked before you pay
What differs between Liraglutide and Tirzepatide
The lipid is where these two differ most. Liraglutide carries palmitic acid, a C16 monoacid, joined to lysine 26 by a single gamma-glutamate; tirzepatide hangs a C20 diacid from lysine 20 on a gamma-glutamate and a pair of AEEA spacers. The chains differ too: liraglutide is GLP-1 (7-37) with one substitution, arginine for lysine 34, ending like the native peptide in a free glycine acid, while tirzepatide is built on the GIP sequence, 39 residues long with two Aib and an amide at its end. In average mass, tirzepatide is 4,813.5 and liraglutide 3,751.3.
| Detail | Liraglutide | Tirzepatide |
|---|---|---|
| Best per mg, by the box | $0.523 per mg (LIR30) | $0.305 per mg (TR60) |
| Best per mg, special order included | $0.523 per mg (LIR30) | $0.276 per mg (TR120, 50 boxes) |
| Price per box sold singly | $36.36 to $156.86 | $44.20 to $182.84 |
| In 50-box lots, per box | None | $33.40 to $331.38 |
| Strengths offered | 3: 5mg, 10mg, 30mg | 12: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 45mg, 50mg, 60mg, 80mg, 100mg, 120mg |
| Highest price per mg | $0.727 per mg (LIR5) | $0.668 per mg (TR5, 50 boxes) |
| On the shelf today | 0 of 3 strengths | 3 of 12 strengths |
| Range | GLP-1 & Metabolic | GLP-1 & Metabolic |
| Also called | NN2211 and NNC 90-1170 | GLP-2 TZ, GLP-2 Tirz and LY3298176 |
| Form | Lyophilised powder | Lyophilised powder |
| Molecular weight | 3,751.3 g/mol | 4,813.5 g/mol |
| Formula | C172 |
C225 |
| CAS number | 204656-20-2 | 2023788-19-2 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Each line’s own page: Liraglutide and Tirzepatide. Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold; stock as this page was opened. Counting special-order lines, sold in 50-box lots, the lowest for Tirzepatide is $0.276 per mg (120mg, TR120); for Liraglutide it is still LIR30, made to order by the single box, at $0.523 per mg.
| Strength | Liraglutide | Tirzepatide |
|---|---|---|
| 5mg | $0.727 per mg (LIR5, made to order) | $0.668 per mg (lower) (TR5, special order, 50 boxes) |
| 10mg | $0.603 per mg (LIR10, made to order) | $0.442 per mg (lower) (TR10, made to order) |
| 30mg | $0.523 per mg (LIR30, made to order) | $0.330 per mg (lower) (TR30, in stock) |
Every strength of both
Compared elsewhere
Semaglutide vs Liraglutide
At 30mg: $0.301 per mg against $0.523; 7 strengths against 3.
Retatrutide vs Tirzepatide
At 60mg: $0.453 per mg against $0.305; 10 strengths against 12.
Tirzepatide vs Semaglutide
At 30mg: $0.330 per mg against $0.301; 12 strengths against 7.
Questions
What is the difference between Liraglutide and Tirzepatide?
The lipid is where these two differ most. Liraglutide carries palmitic acid, a C16 monoacid, joined to lysine 26 by a single gamma-glutamate; tirzepatide hangs a C20 diacid from lysine 20 on a gamma-glutamate and a pair of AEEA spacers.
Which registry numbers and codes identify liraglutide and tirzepatide?
Liraglutide is CAS 204656-20-2 (FDA UNII 839I73S42A), once coded NN2211 and NNC 90-1170, named in WHO’s proposed list 87; liraglutide is also its USAN and JAN. Tirzepatide is CAS 2023788-19-2 (UNII OYN3CCI6QE), once coded LY3298176, named in list 120. Each line’s identity is its mass with the lipid attached: 3,751.3 for liraglutide, 4,813.5 for tirzepatide.
Which is cheaper per mg, Liraglutide or Tirzepatide?
Strength for strength, Tirzepatide costs less per mg at the two strengths both sell by the single box: at 10mg $0.442 per mg against $0.603 (TR10, LIR10), at 30mg $0.330 per mg against $0.523 (TR30, LIR30).
What are the molecular weights of Liraglutide and Tirzepatide?
Liraglutide’s calculated average mass is 3,751.3 g/mol and Tirzepatide’s 4,813.5 g/mol, 1,062.2 apart; in electrospray the ions come at m/z 1251.4 and 938.8 (3+ and 4+) for Liraglutide against 1605.5 and 1204.4 (3+ and 4+) for Tirzepatide. On each certificate the measured mass is matched to the line’s calculated average mass, within about one unit, as how to read a peptide COA sets out.
Are Liraglutide and Tirzepatide made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, matched to the calculated figure on each sheet. The retest date is on the batch record. What differs is each molecule’s own chemistry, described on its compound page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.