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Home / Comparisons / Semaglutide vs Tirzepatide

Semaglutide vs Tirzepatide

Tirzepatide is cheaper per mg here: $0.218 per mg at its best-priced strength (TR30) against $0.283 per mg for Semaglutide (SM50), 23 percent less. Semaglutide is offered in 7 strengths (5mg to 50mg), Tirzepatide in 12 (5mg to 120mg); 4 and 5 of those are on the shelf today.

Prices and stock checked · USD per box of ten · freight included from $1,000.00 an order · COA per batch · research use only

Semaglutide is a 31-residue GLP-1 analogue with a C18 diacid on lysine 26; tirzepatide is a 39-residue GIP-based chain with a C20 diacid on lysine 20. Per milligram they sit in the same class and both are made to the same release limits, so the buying decision usually comes down to which strengths are on the shelf and the per-milligram figure at the vial size the laboratory actually uses. Both have one tryptophan and no methionine, so their certificates read alike.

SemaglutideTirzepatide
RangeGLP-1 & MetabolicGLP-1 & Metabolic
Strengths offered7: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg12: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 45mg, 50mg, 60mg, 80mg, 100mg, 120mg
Price per box of ten$24.93 to $141.28$17.66 to $331.38
Best price per mg$0.283 per mg (SM50)$0.218 per mg (TR30)
Dearest price per mg$0.499 per mg (SM5)$0.353 per mg (TR5)
On the shelf today4 of 7 strengths5 of 12 strengths
FormLyophilised powderLyophilised powder
Average mass4113.64813.5
CAS number910463-68-22023788-19-2
Release limitPurity ≥ 98.0 % by RP-HPLCPurity ≥ 98.0 % by RP-HPLC

Every strength of both

CodeCompoundStrengthPer boxPer unitStock
SM5Semaglutide5mg x 10 vials$24.93$0.499 per mgLow stock
SM10Semaglutide10mg x 10 vials$38.44$0.384 per mgIn stock
SM15Semaglutide15mg x 10 vials$50.90$0.339 per mgMade to order, 2 weeks
SM20Semaglutide20mg x 10 vials$64.41$0.322 per mgLow stock
SM30Semaglutide30mg x 10 vials$90.38$0.301 per mgIn stock
SM40Semaglutide40mg x 10 vials$115.31$0.288 per mgMade to order, 2 weeks
SM50Semaglutide50mg x 10 vials$141.28$0.283 per mgMade to order, 2 weeks
TR5Tirzepatide5mg x 10 vials$17.66$0.353 per mgMade to order, 2 weeks
TR10Tirzepatide10mg x 10 vials$25.97$0.260 per mgLow stock
TR15Tirzepatide15mg x 10 vials$38.44$0.256 per mgIn stock
TR20Tirzepatide20mg x 10 vials$51.94$0.260 per mgMade to order, 2 weeks
TR30Tirzepatide30mg x 10 vials$65.44$0.218 per mgLow stock
TR40Tirzepatide40mg x 10 vials$92.45$0.231 per mgLow stock
TR45Tirzepatide45mg x 10 vials$118.42$0.263 per mgMade to order, 2 weeks
TR50Tirzepatide50mg x 10 vials$145.43$0.291 per mgMade to order, 2 weeks
TR60Tirzepatide60mg x 10 vials$172.44$0.287 per mgIn stock
TR80Tirzepatide80mg x 10 vials$225.42$0.282 per mgMade to order, 2 weeks
TR100Tirzepatide100mg x 10 vials$278.40$0.278 per mgMade to order, 2 weeks
TR120Tirzepatide120mg x 10 vials$331.38$0.276 per mgMade to order, 2 weeks

Questions

Which is cheaper per mg, Semaglutide or Tirzepatide?

Tirzepatide, at $0.218 per mg for its best-priced strength (TR30) against $0.283 per mg for Semaglutide (SM50), 23 percent less. Compare at the vial size you will actually use; the gap changes with strength.

Which comes in more strengths?

Tirzepatide, with 12 against 7. Every strength is a separate line with its own code, price and stock state.

Can Semaglutide and Tirzepatide go in one order?

Yes. Any lines can share an order; the minimum is $300 of goods per order, or $100 on a first order, and one sealed box of ten per line. Lines on the shelf ship in 1 to 2 business days; made-to-order lines follow in about two weeks, at no extra freight.

Are they tested to the same specification?

Yes: purity not less than 98.0 percent by RP-HPLC, identity by mass, water content, net content within 5 percent of label, and a retest date, with a certificate of analysis per batch. What differs is what each certificate has to look for, which is set by the molecule and described on each compound’s own page.

Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.