Mazdutide vs Retatrutide
Strength for strength, Retatrutide costs less per mg at the two strengths both are offered in: at 5mg $1.256 per mg against $1.371 (RT5 in 50-box lots, MDT5 in 50-box lots), at 10mg $0.808 per mg against $1.091 (RT10, MDT10 in 50-box lots). By the single box, Retatrutide is the only option, from $0.453 per mg at 60mg (RT60); every Mazdutide line is special order. Mazdutide is offered in 2 strengths (5mg to 10mg), Retatrutide in 10 (5mg to 100mg); Retatrutide has 2 on the shelf today, Mazdutide none (special order, 50-box minimum). The least either takes: one box of RT10 at $80.80, two for a first order’s $100 minimum, against 50 boxes of MDT5, $3,428.00 of goods.
Prices revised · USD per box of ten · freight included to US addresses from $1,000 of goods · COA per batch · research use only · New to us? What can be checked before you pay
What differs between Mazdutide and Retatrutide
Both are lipidated chains of the glucagon family and both arrive as lyophilised powder, but they are built on different backbones and different lengths. Mazdutide is an oxyntomodulin-type chain of 34 residues carrying a fatty diacid; retatrutide is a 39-residue GIP-based chain with a C20 diacid on lysine 17 and Aib at positions 2 and 20. Their masses, 4,563.1 and 4,731.4, sit 168.3 apart. The practical comparison on this list is the per-milligram figure at the vial size each is offered in.
| Detail | Mazdutide | Retatrutide |
|---|---|---|
| Best per mg, by the box | Special order only | $0.453 per mg (RT60) |
| Best per mg, special order included | $1.091 per mg (MDT10, 50 boxes) | $0.419 per mg (RT100, 50 boxes) |
| Price per box sold singly | Special order only | $80.80 to $271.78 |
| In 50-box lots, per box | $68.56 to $109.07 | $62.80 to $418.64 |
| Strengths offered | 2: 5mg, 10mg | 10: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 80mg, 100mg |
| Highest price per mg | $1.371 per mg (MDT5, 50 boxes) | $1.256 per mg (RT5, 50 boxes) |
| On the shelf today | 0 of 2 strengths | 2 of 10 strengths |
| Range | GLP-1 & Metabolic | GLP-1 & Metabolic |
| Also called | IBI-362 | GLP-3 RT, GLP-3 Reta and LY3437943 |
| Form | Lyophilised powder | Lyophilised powder |
| Molecular weight | 4,563.1 g/mol | 4,731.4 g/mol |
| Formula | C210 |
C221 |
| CAS number | 2259884-03-0 | 2381089-83-2 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Each line’s own page: Mazdutide and Retatrutide. Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold; stock as this page was opened. Counting special-order lines, sold in 50-box lots, the lowest figures are $0.419 per mg for Retatrutide (100mg, RT100) and $1.091 per mg for Mazdutide (10mg, MDT10).
| Strength | Mazdutide | Retatrutide |
|---|---|---|
| 5mg | $1.371 per mg (MDT5, special order, 50 boxes) | $1.256 per mg (lower) (RT5, special order, 50 boxes) |
| 10mg | $1.091 per mg (MDT10, special order, 50 boxes) | $0.808 per mg (lower) (RT10, in stock) |
Every strength of both
Compared elsewhere
Mazdutide vs Survodutide
At 10mg: $1.091 per mg against $1.901, both in 50-box lots; 2 strengths against 1.
Retatrutide vs Tirzepatide
At 60mg: $0.453 per mg against $0.305; 10 strengths against 12.
Retatrutide vs Survodutide
At 10mg: $0.808 per mg against $1.901 (Survodutide, 50-box lots); 10 strengths against 1.
Retatrutide vs Semaglutide
At 30mg: $0.553 per mg against $0.301; 10 strengths against 7.
Adipotide vs Retatrutide
At 10mg: $4.336 per mg (Adipotide, 50-box lots) against $0.808; 3 strengths against 10.
Questions
What is the difference between Mazdutide and Retatrutide?
Both are lipidated chains of the glucagon family and both arrive as lyophilised powder, but they are built on different backbones and different lengths. Mazdutide is an oxyntomodulin-type chain of 34 residues carrying a fatty diacid; retatrutide is a 39-residue GIP-based chain with a C20 diacid on lysine 17 and Aib at positions 2 and 20.
Which atoms account for the 168.3 between mazdutide and retatrutide?
Eleven carbons, twenty hydrogens and one oxygen, C11H20O, are what retatrutide’s C221H342N46O68 has over mazdutide’s C210H322N46O67. Both formulas hold 46 nitrogens, although retatrutide’s chain is five residues longer, 39 against 34. Each carries a C20 fatty diacid, while mazdutide, built on oxyntomodulin, has the glucagon family’s tryptophan and no methionine.
Does Mazdutide or Retatrutide share its backbone with another line on this list?
Retatrutide does: tirzepatide is its backbone twin, each 39 residues long and built on GIP; side by side they part company at nine positions, among them the lysine that takes the lipid, 17 in retatrutide and 20 in tirzepatide, and position 13, alpha-methyl-leucine against tirzepatide’s Aib. Mazdutide has no such twin here. It is an analogue of oxyntomodulin, which is glucagon lengthened by eight residues, and the other glucagon-based line, survodutide, runs only to glucagon’s 29.
Which is cheaper per mg, Mazdutide or Retatrutide?
Strength for strength, Retatrutide costs less per mg at the two strengths both are offered in: at 5mg $1.256 per mg against $1.371 (RT5 in 50-box lots, MDT5 in 50-box lots), at 10mg $0.808 per mg against $1.091 (RT10, MDT10 in 50-box lots).
What are the molecular weights of Mazdutide and Retatrutide?
Mazdutide’s calculated average mass is 4,563.1 g/mol and Retatrutide’s 4,731.4 g/mol, 168.3 apart; in electrospray the ions come at m/z 1522.1 and 1141.8 (3+ and 4+) for Mazdutide against 1578.1 and 1183.9 (3+ and 4+) for Retatrutide. On each certificate the measured mass is matched to the line’s calculated average mass, within about one unit, as how to read a peptide COA sets out.
Are Mazdutide and Retatrutide made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, matched to the calculated figure on each sheet. The retest date is on the batch record. What differs is each molecule’s own chemistry, described on its compound page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.