Retatrutide vs Survodutide
At 10mg, the only strength both are offered in, Retatrutide is the cheaper per mg: $0.808 per mg against $1.901 (RT10, SUR10 in 50-box lots). By the single box, Retatrutide is the only option, from $0.453 per mg at 60mg (RT60); every Survodutide line is special order. Retatrutide is offered in 10 strengths (5mg to 100mg), Survodutide in 1; Retatrutide has 2 on the shelf today, Survodutide none (special order, 50-box minimum). The least either takes: one box of RT10 at $80.80, two for a first order’s $100 minimum, against 50 boxes of SUR10, $9,505.00 of goods.
Prices revised · USD per box of ten · freight included to US addresses from $1,000 of goods · COA per batch · research use only · New to us? What can be checked before you pay
What differs between Retatrutide and Survodutide
Ten residues and a backbone apart: retatrutide is a 39-residue chain on a GIP-based sequence, with alpha-methyl-leucine at 13, Aib at 20 and a C20 fatty diacid on lysine 17; survodutide is a 29-residue chain built on the glucagon sequence, with a C18 fatty diacid on a lysine. Both are acylated, so both certificates identify them by the lipidated mass, 4,731.4 against 4,231.7, 499.7 apart. On both, the related substances of note are the des-lipid chain and positional isomers of the acylation, with deamidation on the glutamines, which retatrutide has at 3 and 19.
| Detail | Retatrutide | Survodutide |
|---|---|---|
| Best per mg, by the box | $0.453 per mg (RT60) | Special order only |
| Best per mg, special order included | $0.419 per mg (RT100, 50 boxes) | $1.901 per mg (SUR10, 50 boxes) |
| Price per box sold singly | $80.80 to $271.78 | Special order only |
| In 50-box lots, per box | $62.80 to $418.64 | $190.10 |
| Strengths offered | 10: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 80mg, 100mg | 1: 10mg |
| Highest price per mg | $1.256 per mg (RT5, 50 boxes) | $1.901 per mg (SUR10, 50 boxes) |
| On the shelf today | 2 of 10 strengths | No, special order |
| Range | GLP-1 & Metabolic | GLP-1 & Metabolic |
| Also called | GLP-3 RT, GLP-3 Reta and LY3437943 | BI 456906 |
| Form | Lyophilised powder | Lyophilised powder |
| Molecular weight | 4,731.4 g/mol | 4,231.7 g/mol |
| Formula | C221 |
C192 |
| CAS number | 2381089-83-2 | 2805997-46-8 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Each line’s own page: Retatrutide and Survodutide. Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold; stock as this page was opened. Counting special-order lines, sold in 50-box lots, the lowest figures are $0.419 per mg for Retatrutide (100mg, RT100) and $1.901 per mg for Survodutide (10mg, SUR10).
| Strength | Retatrutide | Survodutide |
|---|---|---|
| 10mg | $0.808 per mg (lower) (RT10, in stock) | $1.901 per mg (SUR10, special order, 50 boxes) |
Every strength of both
Compared elsewhere
Retatrutide vs Tirzepatide
At 60mg: $0.453 per mg against $0.305; 10 strengths against 12.
Mazdutide vs Retatrutide
At 10mg: $1.091 per mg (Mazdutide, 50-box lots) against $0.808; 2 strengths against 10.
Retatrutide vs Semaglutide
At 30mg: $0.553 per mg against $0.301; 10 strengths against 7.
Mazdutide vs Survodutide
At 10mg: $1.091 per mg against $1.901, both in 50-box lots; 2 strengths against 1.
Adipotide vs Retatrutide
At 10mg: $4.336 per mg (Adipotide, 50-box lots) against $0.808; 3 strengths against 10.
Questions
What is the difference between Retatrutide and Survodutide?
Ten residues and a backbone apart: retatrutide is a 39-residue chain on a GIP-based sequence, with alpha-methyl-leucine at 13, Aib at 20 and a C20 fatty diacid on lysine 17; survodutide is a 29-residue chain built on the glucagon sequence, with a C18 fatty diacid on a lysine.
Which codes and registry numbers identify retatrutide and survodutide?
Each is identified by its mass as the lipidated peptide: retatrutide, CAS 2381089-83-2, at 4,731.4, and survodutide, CAS 2805997-46-8, at 4,231.7. Retatrutide, the INN from WHO Proposed INN List 128, was coded LY3437943, and FDA’s GSRS holds it as UNII NOP2Y096GV, with its sodium salt filed apart as UNII LQ42M82ZU6; survodutide’s sheet gives its code, BI 456906. GLP-3 RT, the nickname some shops give retatrutide, is not a name on the FDA register.
Where are the non-standard residues and the lipid in each chain?
Retatrutide has three residues outside the twenty coded amino acids, an Aib at 2 and another at 20 and an alpha-methyl-leucine at 13, and its C20 diacid is carried on lysine 17 by a gamma-glutamate plus one polyethylene-glycol spacer. Survodutide’s sheet names one at position 2, 1-aminocyclobutane-1-carboxylic acid, where retatrutide has Aib, and its C18 diacid is joined to a lysine through a linker.
Which is cheaper per mg, Retatrutide or Survodutide?
At 10mg, the only strength both are offered in, Retatrutide is the cheaper per mg: $0.808 per mg against $1.901 (RT10, SUR10 in 50-box lots).
What are the molecular weights of Retatrutide and Survodutide?
Retatrutide’s calculated average mass is 4,731.4 g/mol and Survodutide’s 4,231.7 g/mol, 499.7 apart; in electrospray the ions come at m/z 1578.1 and 1183.9 (3+ and 4+) for Retatrutide against 1411.6 and 1058.9 (3+ and 4+) for Survodutide. On each certificate the measured mass is matched to the line’s calculated average mass, within about one unit, as how to read a peptide COA sets out.
Are Retatrutide and Survodutide made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, matched to the calculated figure on each sheet. The retest date is on the batch record. What differs is each molecule’s own chemistry, described on its compound page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.