Retatrutide vs Semaglutide
Strength for strength, Semaglutide costs less per mg at the three strengths both sell by the single box: at 10mg $0.384 per mg against $0.530 (SM10, RT10), at 20mg $0.322 per mg against $0.467 (SM20, RT20), at 30mg $0.301 per mg against $0.447 (SM30, RT30). Retatrutide is offered in 10 strengths (5mg to 100mg), Semaglutide in 7 (5mg to 50mg); 3 and 3 of those are on the shelf today.
Prices revised · USD per box of ten · freight included from $1,000 of goods · COA per batch · research use only
| Detail | Retatrutide | Semaglutide |
|---|---|---|
| Best per mg, by the box | $0.428 per mg (RT60) | $0.301 per mg (SM30) |
| Best per mg, special order included | $0.419 per mg (RT100, 50 boxes) | $0.283 per mg (SM50, 50 boxes) |
| Price per box of ten | $52.98 to $418.64 | $24.93 to $141.28 |
| Strengths offered | 10: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 80mg, 100mg | 7: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg |
| Dearest price per mg | $0.644 per mg (RT5, 50 boxes) | $0.499 per mg (SM5) |
| On the shelf today | 3 of 10 strengths | 3 of 7 strengths |
| Range | GLP-1 & Metabolic | GLP-1 & Metabolic |
| Form | Lyophilised powder | Lyophilised powder |
| Average mass | 4,731.4 g/mol | 4,113.6 g/mol |
| CAS number | 2381089-83-2 | 910463-68-2 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Two acylated peptides of the glucagon family on different backbones. Semaglutide is a 31-residue analogue of human GLP-1 (7-37) with Aib at position 8, arginine at 34 and a C18 fatty diacid on lysine 26; retatrutide is a 39-residue chain on a GIP-type backbone with Aib at 2 and 20, alpha-methyl-leucine at 13 and a C20 fatty diacid on lysine 17, ending in an amide. Both arrive as lyophilised powder in boxes of ten, both elute late on reverse phase, and on each certificate the identity line is the mass with the lipid attached.
Each line’s own page: Retatrutide and Semaglutide. Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold (neither at a tie); stock as this page was opened. Counting special-order lines, sold in 50-box lots, the lowest figures are $0.283 per mg for Semaglutide (50mg, SM50) and $0.419 per mg for Retatrutide (100mg, RT100).
| Strength | Retatrutide | Semaglutide |
|---|---|---|
| 5mg | $0.644 per mg (RT5, special order, 50 boxes) | $0.499 per mg (lower) (SM5, low stock) |
| 10mg | $0.530 per mg (RT10, made to order) | $0.384 per mg (lower) (SM10, made to order) |
| 15mg | $0.492 per mg (RT15, made to order) | $0.339 per mg (lower) (SM15, special order, 50 boxes) |
| 20mg | $0.467 per mg (RT20, made to order) | $0.322 per mg (lower) (SM20, low stock) |
| 30mg | $0.447 per mg (RT30, low stock) | $0.301 per mg (lower) (SM30, in stock) |
| 40mg | $0.436 per mg (RT40, low stock) | $0.288 per mg (lower) (SM40, special order, 50 boxes) |
| 50mg | $0.432 per mg (RT50, special order, 50 boxes) | $0.283 per mg (lower) (SM50, special order, 50 boxes) |
Every strength of both
Compared elsewhere
The same two lines against the others they are usually weighed with.
Adipotide vs Retatrutide
Adipotide against Retatrutide: price per mg, strengths and what differs on the certificate.
Mazdutide vs Retatrutide
Mazdutide against Retatrutide: price per mg, strengths and what differs on the certificate.
Retatrutide vs Survodutide
Retatrutide against Survodutide: price per mg, strengths and what differs on the certificate.
Tirzepatide vs Retatrutide
Tirzepatide against Retatrutide: price per mg, strengths and what differs on the certificate.
Cagrilintide vs Semaglutide
Cagrilintide against Semaglutide: price per mg, strengths and what differs on the certificate.
Semaglutide vs Liraglutide
Semaglutide against Liraglutide: price per mg, strengths and what differs on the certificate.
Questions
Which is cheaper per mg, Retatrutide or Semaglutide?
Strength for strength, Semaglutide costs less per mg at the three strengths both sell by the single box: at 10mg $0.384 per mg against $0.530 (SM10, RT10), at 20mg $0.322 per mg against $0.467 (SM20, RT20), at 30mg $0.301 per mg against $0.447 (SM30, RT30). Counting special-order lines, sold in 50-box lots, the lowest figures are $0.283 per mg for Semaglutide (50mg, SM50) and $0.419 per mg for Retatrutide (100mg, RT100).
How do I tell Retatrutide and Semaglutide apart on a certificate?
By the mass line. Retatrutide’s calculated average mass is 4,731.4 g/mol and Semaglutide’s 4,113.6 g/mol, 617.8 apart; in electrospray expect m/z 1578.1 and 1183.9 (3+ and 4+) for Retatrutide against 1372.2 and 1029.4 (3+ and 4+) for Semaglutide. A measured mass within about one unit of one figure reads as that molecule; a gap of 16, 18 or 2 has a known cause, set out in how to read a peptide COA.
Can Retatrutide and Semaglutide go in one order?
Yes. Any lines can share an order, and the order minimum is counted across all of them: $100 on a first order, $300 on the second, $500 on the third and $1,000 from the fourth order on. Lines on the shelf ship in 1 to 2 business days; made-to-order lines follow in about two weeks, at no extra freight. Strengths marked special order in the table above are brought in on a 50-box minimum rather than held in stock.
Are Retatrutide and Semaglutide made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, read against the calculated figure on each sheet. The retest date is on the batch record. What differs is what each certificate has to look for, which is set by the molecule and described on each compound’s own page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.