MOTS-c wholesale
Bulk peptide powder in 10-vial kits, for sale in the USA and abroad: price and cost per mg
About MOTS-c
Mitochondrial-derived 16-residue peptide, MRWQEMGYIFYPRKLR. 4 vial strengths, 10mg to 40mg, from $78.32 to $267.43 per box of ten, in US dollars. Made to order in about four weeks or special order (50-box minimum), as marked.
Documents Specification sheet Verify a batch How to read the certificate What the purity figure means The mass result, explained
MOTS-c price per box, per vial and per mg
| Code | Strength | Per box | Per vial | Per mg | Stock | Order |
|---|---|---|---|---|---|---|
| MS10 | 10mg x 10 vials | $78.32 | $7.83 | $0.783 per mg | Made to order, 4 weeks | |
| MS15 | 15mg x 10 vials | $110.04 | $11.00 | $0.734 per mg | Special order, 50-box minimum | |
| MS20 | 20mg x 10 vials | $141.13 | $14.11 | $0.706 per mg | Made to order, 4 weeks | |
| MS40 | 40mg x 10 vials | $267.43 | $26.74 | Lowest $0.669 per mg | Made to order, 4 weeks |
Ships from the USA: to US addresses at our risk until delivered (DAP), freight included from $1,000 of goods; to Canada and most other countries through the desk · on-shelf lines leave in 1 to 2 business days, then 1 to 3 business days in US transit · COA per batch · proforma in USD, paid by card, Wise, e-Transfer (Canada), Bitcoin or USDT · prices revised
Stock key
- In stock
- on the shelf, leaves in 1 to 2 business days once payment clears
- Low stock
- on the shelf and running low; leaves in 1 to 2 business days
- Ships in 1 week
- on its way in
- Ships in 2 weeks
- on order
- Made to order, 4 weeks
- made for the order, about four weeks
- Special order, 50-box minimum
- brought in on a 50-box minimum rather than held in stock; the desk confirms the date before you pay
Prices are in US dollars per sealed box. Per unit is the box price over the milligrams, millilitres or units in the box.
MOTS-c in brief
MOTS-c comes in 4 strengths from 10mg to 40mg per vial, each a sealed box of ten, from $78.32 to $267.43 a box for the strengths sold singly. Per mg the spread is narrow: MS40 (40mg x 10 vials) works out at $0.669 per mg against $0.783 per mg for MS10 (10mg x 10 vials), 15 percent less for the same mg, because the vial, the fill and the testing cost about the same whatever the vial holds.
Nothing is on the shelf today. MS10, MS20 and MS40 are made to order, about four weeks, in any quantity. MS15 is special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.
What MOTS-c is
MOTS-c is a 16-residue peptide, MRWQEMGYIFYPRKLR, whose sequence is encoded within the mitochondrial 12S ribosomal RNA gene, an unusual origin for a peptide. Average mass 2174.6, formula C101H152N28O22S2. It is made synthetically.
Two methionines, at positions 1 and 6, and a tryptophan at 3 make it one of the more oxidation-prone chains on this list: the sulfoxides are the related substances to expect, and a batch stored warm or in light forms more of them. It is basic, with three arginines and a lysine, and moderately hydrophobic. Keep cold and dark.
Registry and identity
- MOTS-c is UniProt entry A0A0C5B5G6 (MOTSC_HUMAN), encoded in the mitochondrial MT-RNR1 gene, and FDA's GSRS holds it as mitochondria-derived peptide MOTS-c, UNII A5CV6JFB78, CAS 1627580-64-6, PubChem CID 146675088. UniProt, FDA GSRS
- FDA also files an N-acetylated MOTS-c (UNII 9ND3NG2FKG) that would weigh about 2216.7, 42.0 more than the free-amine chain on this page. FDA GSRS
- At high resolution the MOTS-c monoisotopic ions are at m/z 725.377 (3+) and 544.284 (4+), from a monoisotopic mass of 2173.108. PubChem, NIST
A listing in these registers identifies a substance; it is not an approval of this line.
MOTS-c beside SS-31 and NAD+
MOTS-c works out at $0.669 per mg at 40mg (MS40), its lowest by the single box. Its neighbours, on price alone: SS-31 at $0.771 per mg at 50mg (2S50), 639.8 g/mol, set side by side in MOTS-c vs SS-31; NAD+ at $0.012 per mg at 500mg (NJ500), 663.4 g/mol.
Reading a MOTS-c certificate of analysis (COA)
Identity by mass. Average mass 2174.6 (C101H152N28O22S2). In electrospray the protonated ions come near m/z 2175.6 (singly charged), m/z 1088.3 (doubly charged), m/z 725.9 (3x charged); on our certificates the measured mass is matched to the calculated average mass, within about one unit.
- Oxidation: 2 methionines, which oxidise to the sulfoxide; 1 tryptophan, which oxidises to kynurenine and hydroxy forms under light. Each sulfoxide makes the chain 16 heavier; kynurenine makes it 4 heavier and a hydroxy tryptophan 16.
- Deamidation: 1 glutamine. The deamidated form is 0.984 heavier and a little more negatively charged, inside the tolerance of the average-mass line; telling it apart takes a high-resolution mass, which the certificate does not carry.
- Charge: near neutral pH about +3, basic.
Worked out from what the sheet holds for this line; the batch certificate is the record. How to read one, and verify a batch number.
Buy MOTS-c in bulk
MOTS-c is sold in bulk by the sealed box of ten vials, and every account starts at list price. Two discounts can lower it, the size of one order (from $5,000 of goods) or the account’s tier (from lifetime paid spend), and the better one applies, never both. Priced below on MS40, 40mg x 10 vials, the best-priced strength.
| Discount | Earned by | Off goods | MS40 per box | Per mg |
|---|---|---|---|---|
| List | Every account, any order | none | $267.43 | $0.669 |
| Order size | $5,000 of goods in one order | 5% | $254.06 | $0.635 |
| Order size | $10,000 of goods in one order | 10% | $240.69 | $0.602 |
| Order size | $20,000 of goods in one order | 15% | $227.32 | $0.568 |
| Order size | $50,000 of goods in one order | 20% | $213.94 | $0.535 |
| Silver tier | $5,000 lifetime paid spend | 3% | $259.41 | $0.649 |
| Gold tier | $15,000 lifetime paid spend | 6% | $251.38 | $0.628 |
| Platinum tier | $50,000 lifetime paid spend | 10% | $240.69 | $0.602 |
| Diamond tier | $100,000 lifetime paid spend | 15% | $227.32 | $0.568 |
Thresholds in USD on goods, before freight; the discount is worked out at checkout and shown on the proforma.
Specification
The limits this compound is supplied to.
| Purity | ≥ 98.0 % (RP-HPLC, 220 nm, area normalisation) |
|---|---|
| Identity | ESI-MS against a calculated average mass of 2174.6 |
| Any single related substance | ≤ 1.0 % |
| Water | ≤ 8.0 % (Karl Fischer) |
| Acetate | ≤ 15.0 % (ion chromatography), as the acetate salt |
| Residual solvents | Acetonitrile ≤ 410 ppm; TFA ≤ 1.0 % |
| Net content | Label claim ± 5 % |
| Closure | 2 mL glass vial, bromobutyl stopper, aluminium flip-off seal |
| Storage | −20 °C, dark and dry; brief ambient transit tolerated |
| Shelf life | 24 months from manufacture; retest date on the batch record |
Order MOTS-c
One box of MS10, 10mg x 10 vials, $78.32 a box. Every strength.
Questions about MOTS-c
What are MOTS-c’s sequence, formula, molecular weight and CAS number?
MRWQEMGYIFYPRKLR, 16 residues, UniProt A0A0C5B5G6 (MOTSC_HUMAN): C101H152N28O22S2, molecular weight (average mass) 2,174.6, CAS 1627580-64-6 (FDA GSRS UNII A5CV6JFB78). The N-acetylated MOTS-c that FDA also files, UNII 9ND3NG2FKG, is a different substance, about 42.0 heavier.
Which lines bracket MOTS-c by mass?
AOD9604 below, at 1,815.1, and adipotide above, at 2,555.2, so MOTS-c sits in a gap of 740.1 between them, 359.5 heavier than AOD9604 and 380.6 lighter than adipotide, with no other printed molecular weight within 350 of its 2,174.6. Of the three it is the one with no disulfide, since its sixteen residues hold no cysteine, and its two sulfur atoms are the methionines at 1 and 6.
How much does MOTS-c cost?
From $78.32 a sealed box of 10 vials, up to $267.43 for the largest strength sold singly, which works out at $0.669 per mg at its best-priced size. MS15 is special order, 50 boxes at least, at $110.04 a box. To a US address, freight is included from $1,000 of goods; below that it is the carrier’s rate for the carton or a flat $35.00, and to another country the desk quotes it; either way the figure is on the proforma before you pay. Every strength and its price per vial is in this page’s price table.
Which MOTS-c size is cheapest per mg?
MS40, 40mg x 10 vials, at $0.669 per mg, which is 15 percent less per mg than MS10, at $0.783 per mg. Larger vials cost less per mg across this range, so match the vial to the size of the work first, then compare per mg.
Can I buy a single vial of MOTS-c?
No. One sealed box of ten vials is the smallest quantity of a regular line; for MOTS-c that is MS10, 10mg x 10 vials, at $78.32. A first order must reach $100 of goods, so MS10 alone takes two boxes ($156.64) or one box beside other lines. MS15 is special order and takes a minimum of 50 boxes. A box is sealed at fill with its batch number on it, and splitting one would break the link between the vials and their certificate.
Which MOTS-c strengths are in stock today?
None today. MS10, MS20 and MS40 are made to order, about four weeks, in any quantity. MS15 is special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.
How is MOTS-c stored?
At minus 20 degrees Celsius, dark and dry. Lyophilised powder tolerates a short spell at ambient temperature in transit, which is why boxes ship without ice. Storage and handling.
What is in a box of MOTS-c?
Ten sealed vials of one strength, each labelled with the product code, the strength and the batch number; the trade also calls a box a 10-vial kit. MOTS-c is supplied as a powder in a sealed glass vial and in no other presentation. Its specification sheet carries the catalogue name, MOTS-C. Boxes are not split.
Is a certificate of analysis (COA) provided for MOTS-c?
Yes. For MOTS-c the batch certificate reports its purity, net content and identity by mass spectrometry. The other lines on this page are the specification it is made to, and the desk answers for them on a particular batch. The certificate is sent with the shipment, and again on request, and any batch number can be verified on the certificate page.
Is this for human use?
No. Everything here is supplied for laboratory research only, to trade accounts, and is not for human or animal consumption. The research-use page sets out who can buy and what is not sold.