PNC27 wholesale
Bulk peptide powder in 10-vial kits, for sale in the USA and abroad: price and cost per mg
About PNC27
Synthetic 32-residue peptide: a segment of p53 fused to a 17-residue membrane residency peptide, PPLSQETFSD LWKLLKKWKM RRNQFWVKVQ RG. 2 vial strengths, 5mg to 10mg, from $52.98 to $90.38 per box of ten, in US dollars. Special order, with a 50-box minimum.
Documents Specification sheet Verify a batch How to read the certificate What the purity figure means The mass result, explained
PNC27 price per box, per vial and per mg
| Code | Strength | Per box | Per vial | Per mg | Stock | Order |
|---|---|---|---|---|---|---|
| PNC275 | 5mg x 10 vials | $52.98 | $5.30 | $1.060 per mg | Special order, 50-box minimum | |
| PNC2710 | 10mg x 10 vials | $90.38 | $9.04 | Lowest, 50 boxes $0.904 per mg | Special order, 50-box minimum |
Ships from the USA: to US addresses at our risk until delivered (DAP), freight included from $1,000 of goods; to Canada and most other countries through the desk · on-shelf lines leave in 1 to 2 business days, then 1 to 3 business days in US transit · COA per batch · proforma in USD, paid by card, Wise, e-Transfer (Canada), Bitcoin or USDT · prices revised
Stock key
- In stock
- on the shelf, leaves in 1 to 2 business days once payment clears
- Low stock
- on the shelf and running low; leaves in 1 to 2 business days
- Ships in 1 week
- on its way in
- Ships in 2 weeks
- on order
- Made to order, 4 weeks
- made for the order, about four weeks
- Special order, 50-box minimum
- brought in on a 50-box minimum rather than held in stock; the desk confirms the date before you pay
Prices are in US dollars per sealed box. Per unit is the box price over the milligrams, millilitres or units in the box.
PNC27 in brief
PNC27 comes in 2 strengths from 5mg to 10mg per vial, each a sealed box of ten, from $52.98 to $90.38 a box. Per mg the spread is narrow: PNC2710 (10mg x 10 vials) works out at $0.904 per mg against $1.060 per mg for PNC275 (5mg x 10 vials), 15 percent less for the same mg, because the vial, the fill and the testing cost about the same whatever the vial holds.
Nothing is held on the shelf: every strength is special order, brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.
What PNC27 is
PNC-27 is a chimeric synthetic peptide that joins a segment of the p53 protein to the 17-residue membrane residency peptide (MRP), derived from the Antennapedia homeodomain. The result is a long, amphipathic, strongly basic chain of two very different halves.
Penetratin contributes tryptophans and several lysines and arginines, so the peptide is light-sensitive and takes many charges in electrospray. Its certificate is a peptide certificate, identity by mass and purity by reverse-phase HPLC, and the residues that can oxidise are its tryptophans and the one methionine its formula’s sulfur belongs to. Store dark and cold.
PNC27 beside FOXO4-DRI and Adipotide
PNC27 works out at $0.904 per mg at 10mg (PNC2710, in 50-box lots), its lowest. Its neighbours: FOXO4-DRI at $2.057 per mg at 10mg (F410, in 50-box lots), 5,358.2 g/mol; Adipotide at $4.336 per mg at 10mg (AP10, in 50-box lots), 2,555.2 g/mol, another two-part chimera: the disulfide ring CKGGRAKDC, a Gly-Gly bridge, then KLAKLAKKLAKLAK made wholly of D-residues.
Reading a PNC27 certificate of analysis (COA)
Identity by mass. Average mass 4031.8 (C188H293N53O44S). In electrospray the protonated ions come near m/z 4032.8 (singly charged), m/z 2016.9 (doubly charged), m/z 1344.9 (3x charged), m/z 1009.0 (4x charged); on our certificates the measured mass is matched to the calculated average mass, within about one unit.
- Its tryptophans and its one methionine can oxidise, the methionine to the sulfoxide; store in the dark.
Worked out from what the sheet holds for this line; the batch certificate is the record. How to read one, and verify a batch number.
Buy PNC27 in bulk
PNC27 is sold in bulk by the sealed box of ten vials, and every account starts at list price. Two discounts can lower it, the size of one order (from $5,000 of goods) or the account’s tier (from lifetime paid spend), and the better one applies, never both. Priced below on PNC2710, 10mg x 10 vials, the best-priced strength.
| Discount | Earned by | Off goods | PNC2710 per box | Per mg |
|---|---|---|---|---|
| List | Every account, any order | none | $90.38 | $0.904 |
| Order size | $5,000 of goods in one order | 5% | $85.86 | $0.859 |
| Order size | $10,000 of goods in one order | 10% | $81.34 | $0.813 |
| Order size | $20,000 of goods in one order | 15% | $76.82 | $0.768 |
| Order size | $50,000 of goods in one order | 20% | $72.30 | $0.723 |
| Silver tier | $5,000 lifetime paid spend | 3% | $87.67 | $0.877 |
| Gold tier | $15,000 lifetime paid spend | 6% | $84.96 | $0.850 |
| Platinum tier | $50,000 lifetime paid spend | 10% | $81.34 | $0.813 |
| Diamond tier | $100,000 lifetime paid spend | 15% | $76.82 | $0.768 |
Thresholds in USD on goods, before freight; the discount is worked out at checkout and shown on the proforma.
Specification
The limits this compound is supplied to.
| Purity | ≥ 98.0 % (RP-HPLC, 220 nm, area normalisation) |
|---|---|
| Identity | ESI-MS against a calculated average mass of 4031.8 |
| Any single related substance | ≤ 1.0 % |
| Water | ≤ 8.0 % (Karl Fischer) |
| Acetate | ≤ 15.0 % (ion chromatography), as the acetate salt |
| Residual solvents | Acetonitrile ≤ 410 ppm; TFA ≤ 1.0 % |
| Net content | Label claim ± 5 % |
| Closure | 2 mL glass vial, bromobutyl stopper, aluminium flip-off seal |
| Storage | −20 °C, dark and dry; brief ambient transit tolerated |
| Shelf life | 24 months from manufacture; retest date on the batch record |
Order PNC27
50 boxes of PNC275, 5mg x 10 vials, $52.98 a box. Every strength.
Questions about PNC27
Is any other line built the way PNC27 is?
Yes: FOXO4-DRI. Each joins a piece of a larger protein to a second, basic segment: PNC27 puts a stretch of p53 in front of the 17-residue membrane residency peptide from the Antennapedia homeodomain, a 32-residue chain of 4,031.8, and FOXO4-DRI joins a piece of FOXO4, the forkhead protein, to an arginine-rich segment, 46 residues weighing 5,358.2, every one a D-amino acid set in reversed order. Both are strongly basic and take many charges in electrospray; PNC27’s tryptophans and its one methionine can oxidise, while FOXO4-DRI’s D configuration rests on its synthesis record.
How much does PNC27 cost?
It is sold only by special order, 50 boxes per strength, from $52.98 a sealed box of 10 vials, up to $90.38 for the largest strength, which works out at $0.904 per mg at its best-priced size. The smallest order is 50 boxes of PNC275, $2,649.00 of goods, with freight included to a US address. Every strength and its price per vial is in this page’s price table.
Which PNC27 size is cheapest per mg?
PNC2710, 10mg x 10 vials, at $0.904 per mg, which is 15 percent less per mg than PNC275, at $1.060 per mg. Larger vials cost less per mg across this range, so match the vial to the size of the work first, then compare per mg.
Can I buy a single vial of PNC27?
No, and not a single box either. PNC27 is a special-order line, brought in on a 50-box minimum rather than held in stock, so the smallest order is 50 sealed boxes of one strength: for PNC275, 5mg x 10 vials, that is 50 boxes at $52.98, $2,649.00 of goods. A box is sealed at fill with its batch number on it, and splitting one would break the link between the vials and their certificate.
Which PNC27 strengths are in stock today?
None today. PNC275 and PNC2710 are special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.
How is PNC27 stored?
At minus 20 degrees Celsius, dark and dry. Lyophilised powder tolerates a short spell at ambient temperature in transit, which is why boxes ship without ice. Storage and handling.
What is in a box of PNC27?
Ten sealed vials of one strength, each labelled with the product code, the strength and the batch number; the trade also calls a box a 10-vial kit. PNC27 is supplied as a powder in a sealed glass vial and in no other presentation. Boxes are not split.
Is a certificate of analysis (COA) provided for PNC27?
Yes. For PNC27 the batch certificate reports its purity, net content and identity by mass spectrometry. The other lines on this page are the specification it is made to, and the desk answers for them on a particular batch. The certificate is sent with the shipment, and again on request, and any batch number can be verified on the certificate page.
Is this for human use?
No. Everything here is supplied for laboratory research only, to trade accounts, and is not for human or animal consumption. The research-use page sets out who can buy and what is not sold.