SS-31 wholesale
SS-31, also called elamipretide. Bulk peptide powder in 10-vial kits, for sale in the USA and abroad: price and cost per mg
About SS-31
Tetrapeptide amide with D-arginine and dimethyltyrosine (Dmt), D-Arg-Dmt-Lys-Phe-NH2. 2 vial strengths, 10mg to 50mg, from $88.90 to $385.62 per box of ten, in US dollars. Made to order in about four weeks.
Documents Specification sheet Verify a batch How to read the certificate What the purity figure means The mass result, explained
SS-31 price per box, per vial and per mg
| Code | Strength | Per box | Per vial | Per mg | Stock | Order |
|---|---|---|---|---|---|---|
| 2S10 | 10mg x 10 vials | $88.90 | $8.89 | $0.889 per mg | Made to order, 4 weeks | |
| 2S50 | 50mg x 10 vials | $385.62 | $38.56 | Lowest $0.771 per mg | Made to order, 4 weeks |
Ships from the USA: to US addresses at our risk until delivered (DAP), freight included from $1,000 of goods; to Canada and most other countries through the desk · on-shelf lines leave in 1 to 2 business days, then 1 to 3 business days in US transit · COA per batch · proforma in USD, paid by card, Wise, e-Transfer (Canada), Bitcoin or USDT · prices revised
Stock key
- In stock
- on the shelf, leaves in 1 to 2 business days once payment clears
- Low stock
- on the shelf and running low; leaves in 1 to 2 business days
- Ships in 1 week
- on its way in
- Ships in 2 weeks
- on order
- Made to order, 4 weeks
- made for the order, about four weeks
- Special order, 50-box minimum
- brought in on a 50-box minimum rather than held in stock; the desk confirms the date before you pay
Prices are in US dollars per sealed box. Per unit is the box price over the milligrams, millilitres or units in the box.
SS-31 in brief
SS-31 comes in 2 strengths from 10mg to 50mg per vial, each a sealed box of ten, from $88.90 to $385.62 a box. Per mg the spread is narrow: 2S50 (50mg x 10 vials) works out at $0.771 per mg against $0.889 per mg for 2S10 (10mg x 10 vials), 13 percent less for the same mg, because the vial, the fill and the testing cost about the same whatever the vial holds.
Nothing is on the shelf today: every strength is made to order, about four weeks, in any quantity.
What SS-31 is
SS-31, also called elamipretide, is a synthetic tetrapeptide amide, D-Arg-Dmt-Lys-Phe-NH2, average mass 639.8, where Dmt is 2,6-dimethyltyrosine, a non-coded residue. With a D-arginine at one end, an unnatural tyrosine and an amidated C-terminus, it carries two non-coded residues and no free C-terminal acid.
Alternating basic and aromatic residues give it its amphipathic character. There is nothing in it to oxidise in the usual sense, no methionine or tryptophan, and no asparagine or glutamine to deamidate; only its C-terminal amide can hydrolyse to the free acid, 0.984 heavier. Its certificate reports purity by HPLC, net content and identity by mass. Supplied as the acetate; the residual TFA limit in its specification matters here, because small basic peptides hold TFA strongly, and the desk answers for a particular batch.
Registry and identity
- SS-31, MTP-131 and RX-31 are all codes for elamipretide, the INN from WHO Proposed INN List 113 and also the USAN, which FDA's GSRS files as UNII 87GWG91S09 with CAS 736992-21-5, DrugBank DB11981 and PubChem CID 11764719, keeping Szeto-Schiller peptide among its names. FDA GSRS
- GSRS spells the structure out as D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide, C32H49N9O5, 639.8, with four defined stereocentres and D only at arginine. FDA GSRS
- The salt that holds the USAN is the trihydrochloride, elamipretide hydrochloride (UNII E40WZ3BK2D, CAS 2244098-12-0, PubChem CID 137528200), 749.2 with its three HCl, which make up 14.6 percent of it (worked from that formula). FDA GSRS
- The 2,6-dimethyltyrosine keeps tyrosine's phenol, so unlike many short peptides the chain absorbs near 275 to 280 nm as well as at peptide-bond wavelengths. FDA GSRS
- Three basic sites, the arginine, the lysine and the free N-terminal amine, let it take up to three protons: worked from C32H49N9O5 with NIST isotope masses, [M+H]+ is m/z 640.393, [M+2H]2+ 320.700 and [M+3H]3+ 214.136. PubChem, NIST
A listing in these registers identifies a substance; it is not an approval of this line.
SS-31 beside MOTS-c and Pinealon
SS-31 works out at $0.771 per mg at 50mg (2S50), its lowest by the single box. Its neighbours, on price alone: MOTS-c at $0.669 per mg at 40mg (MS40), 2,174.6 g/mol, set side by side in MOTS-c vs SS-31; Pinealon at $0.322 per mg at 20mg (PL20, in 50-box lots), 418.4 g/mol.
Reading an SS-31 certificate of analysis (COA)
Identity by mass. Average mass 639.8 (C32H49N9O5). In electrospray the protonated ions come near m/z 640.8 (singly charged); on our certificates the measured mass is matched to the calculated average mass, within about one unit.
- Oxidation: no methionine, tryptophan or cysteine in the chain, so oxidised forms are not the impurity to expect.
- Deamidation: no asparagine or glutamine, but the C-terminal amide can hydrolyse to the free acid, 0.984 heavier, inside the tolerance of the average-mass line; telling the acid from the amide takes a high-resolution mass, which the certificate does not carry.
- Charge: near neutral pH about +3, basic.
Worked out from what the sheet holds for this line; the batch certificate is the record. How to read one, and verify a batch number.
Buy SS-31 in bulk
SS-31 is sold in bulk by the sealed box of ten vials, and every account starts at list price. Two discounts can lower it, the size of one order (from $5,000 of goods) or the account’s tier (from lifetime paid spend), and the better one applies, never both. Priced below on 2S50, 50mg x 10 vials, the best-priced strength.
| Discount | Earned by | Off goods | 2S50 per box | Per mg |
|---|---|---|---|---|
| List | Every account, any order | none | $385.62 | $0.771 |
| Order size | $5,000 of goods in one order | 5% | $366.34 | $0.733 |
| Order size | $10,000 of goods in one order | 10% | $347.06 | $0.694 |
| Order size | $20,000 of goods in one order | 15% | $327.78 | $0.656 |
| Order size | $50,000 of goods in one order | 20% | $308.50 | $0.617 |
| Silver tier | $5,000 lifetime paid spend | 3% | $374.05 | $0.748 |
| Gold tier | $15,000 lifetime paid spend | 6% | $362.48 | $0.725 |
| Platinum tier | $50,000 lifetime paid spend | 10% | $347.06 | $0.694 |
| Diamond tier | $100,000 lifetime paid spend | 15% | $327.78 | $0.656 |
Thresholds in USD on goods, before freight; the discount is worked out at checkout and shown on the proforma.
Specification
The limits this compound is supplied to.
| Purity | ≥ 98.0 % (RP-HPLC, 220 nm, area normalisation) |
|---|---|
| Identity | ESI-MS against a calculated average mass of 639.8 |
| Any single related substance | ≤ 1.0 % |
| Water | ≤ 8.0 % (Karl Fischer) |
| Acetate | ≤ 15.0 % (ion chromatography), as the acetate salt |
| Residual solvents | Acetonitrile ≤ 410 ppm; TFA ≤ 1.0 % |
| Net content | Label claim ± 5 % |
| Closure | 2 mL glass vial, bromobutyl stopper, aluminium flip-off seal |
| Storage | −20 °C, dark and dry; brief ambient transit tolerated |
| Shelf life | 24 months from manufacture; retest date on the batch record |
Order SS-31
One box of 2S10, 10mg x 10 vials, $88.90 a box. Every strength.
Questions about SS-31
Is elamipretide the same as SS-31?
Yes. Elamipretide and SS-31 are names for the same thing. Elamipretide is the international non-proprietary name of the tetrapeptide coded SS-31; MTP-131 is another code for it. The certificate and the vial label carry SS-31, which is the name the batch is released under.
What are SS-31’s sequence, formula, molecular weight and CAS number?
D-Arg-Dmt-Lys-Phe-NH2, a tetrapeptide amide whose second residue is 2,6-dimethyltyrosine: C32H49N9O5, molecular weight (average mass) 639.8, CAS 736992-21-5, which FDA’s GSRS files as UNII 87GWG91S09 under the international name elamipretide. The trihydrochloride that holds the USAN is filed apart, under CAS 2244098-12-0; this line is supplied as the acetate.
How much does SS-31 cost?
From $88.90 a sealed box of 10 vials, up to $385.62 for the largest strength sold singly, which works out at $0.771 per mg at its best-priced size. To a US address, freight is included from $1,000 of goods; below that it is the carrier’s rate for the carton or a flat $35.00, and to another country the desk quotes it; either way the figure is on the proforma before you pay. Every strength and its price per vial is in this page’s price table.
Which SS-31 size is cheapest per mg?
2S50, 50mg x 10 vials, at $0.771 per mg, which is 13 percent less per mg than 2S10, at $0.889 per mg. Larger vials cost less per mg across this range, so match the vial to the size of the work first, then compare per mg.
Can I buy a single vial of SS-31?
No. One sealed box of ten vials is the smallest quantity of a regular line; for SS-31 that is 2S10, 10mg x 10 vials, at $88.90. A first order must reach $100 of goods, so 2S10 alone takes two boxes ($177.80) or one box beside other lines. A box is sealed at fill with its batch number on it, and splitting one would break the link between the vials and their certificate.
Which SS-31 strengths are in stock today?
None today. Every strength is made to order, about four weeks, and can be ordered in any quantity.
How is SS-31 stored?
At minus 20 degrees Celsius, dark and dry. Lyophilised powder tolerates a short spell at ambient temperature in transit, which is why boxes ship without ice. Storage and handling.
What is in a box of SS-31?
Ten sealed vials of one strength, each labelled with the product code, the strength and the batch number; the trade also calls a box a 10-vial kit. SS-31 is supplied as a powder in a sealed glass vial and in no other presentation. Boxes are not split.
Is a certificate of analysis (COA) provided for SS-31?
Yes. For SS-31 the batch certificate reports its purity, net content and identity by mass spectrometry. The other lines on this page are the specification it is made to, and the desk answers for them on a particular batch. The certificate is sent with the shipment, and again on request, and any batch number can be verified on the certificate page.
Is this for human use?
No. Everything here is supplied for laboratory research only, to trade accounts, and is not for human or animal consumption. The research-use page sets out who can buy and what is not sold.