BPC-157 vs TB-500 (thymosin beta-4 acetate)
Strength for strength, BPC-157 costs less per mg at the two strengths both sell by the single box: at 5mg $0.764 per mg against $1.428 (BC5, TB5), at 10mg $0.553 per mg against $1.034 (BC10, TB10). BPC-157 is offered in 3 strengths (2mg to 10mg), TB-500 in 3 (2mg to 10mg); 1 and 2 of those are on the shelf today.
Prices revised · USD per box of ten · freight included to US addresses from $1,000 of goods · COA per batch · research use only · New to us? What can be checked before you pay
What differs between BPC-157 and TB-500
BPC-157 is GEPPPGKPADDAGLV, fifteen residues, four of them prolines, with no residue that oxidises or deamidates, so its related substances are synthesis by-products such as a chain one residue short. TB-500 is thymosin beta-4, 43 residues with an acetylated N-terminus; its methionine at 6 gives a sulfoxide, the related substance to expect first, and it has one asparagine and three glutamines to deamidate. The two are also sold together: in a co-formulated vial of their own, BPC-157 + TB-500, and inside the GLOW and KLOW blends.
| Detail | BPC-157 | TB-500 |
|---|---|---|
| Best price per mg | $0.553 per mg (BC10) | $1.034 per mg (TB10) |
| Price per box sold singly | $38.20 to $55.30 | $71.40 to $103.40 |
| In 50-box lots, per box | $22.20 | $28.00 |
| Strengths offered | 3: 2mg, 5mg, 10mg | 3: 2mg, 5mg, 10mg |
| Highest price per mg | $1.110 per mg (BC2, 50 boxes) | $1.428 per mg (TB5) |
| On the shelf today | 1 of 3 strengths | 2 of 3 strengths |
| Range | Repair & Recovery | Repair & Recovery |
| Also called | Bepecin, PL-14736 and PLD-116 | timbetasin |
| Form | Lyophilised powder | Lyophilised powder |
| Molecular weight | 1,419.6 g/mol | 4,963.5 g/mol |
| Formula | C62 |
C212 |
| CAS number | 137525-51-0 | 77591-33-4 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Each line’s own page: BPC-157 and TB-500 (thymosin beta-4 acetate). Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold; stock as this page was opened.
| Strength | BPC-157 | TB-500 |
|---|---|---|
| 2mg | $1.110 per mg (lower) (BC2, special order, 50 boxes) | $1.400 per mg (TB2, special order, 50 boxes) |
| 5mg | $0.764 per mg (lower) (BC5, low stock) | $1.428 per mg (TB5, in stock) |
| 10mg | $0.553 per mg (lower) (BC10, made to order) | $1.034 per mg (TB10, low stock) |
Every strength of both
Sold together
BPC-157 + TB-500
Blend of BPC-157 and Thymosin beta-4 (TB-500)
from $59.10 a box 2 strengths
(made to order)GLOW blend 70mg
Blend of BPC-157, GHK-Cu and Thymosin beta-4
from $154.80 a box 1 strength
(on the shelf)GLOW blend 50mg
Blend of BPC-157, GHK-Cu and Thymosin beta-4
from $119.00 a box 1 strength
(special order)KLOW blend 80mg
Blend of BPC-157, Thymosin beta-4, GHK-Cu and KPV
from $170.80 a box 1 strength
(on the shelf)Compared elsewhere
BPC-157 vs GHK-Cu
$0.553 per mg against $0.052 per mg at best; 3 strengths against 2.
BPC-157 vs KPV
At 10mg: $0.553 per mg against $0.565; 3 strengths against 2.
Thymosin Alpha-1 vs TB-500
At 10mg: $2.170 per mg against $1.034; 3 strengths each.
GHK-Cu vs TB-500
$0.052 per mg against $1.034 per mg at best; 2 strengths against 3.
Questions
What is the difference between BPC-157 and TB-500?
BPC-157 is GEPPPGKPADDAGLV, fifteen residues, four of them prolines, with no residue that oxidises or deamidates, so its related substances are synthesis by-products such as a chain one residue short. TB-500 is thymosin beta-4, 43 residues with an acetylated N-terminus; its methionine at 6 gives a sulfoxide, the related substance to expect first, and it has one asparagine and three glutamines to deamidate.
Is International Peptides’ TB-500 the full thymosin beta-4 chain?
Yes: 43 residues, the chain whose INN is timbetasin (UNII 2D5MRE3SSY, CAS 77591-33-4), average mass 4,963.5. FDA’s record under the name TB-500 (UNII QHK6Z47GTG, CAS 885340-08-9) is a different molecule, the seven-residue fragment Ac-LKKTETQ, at 889.0.
BPC-157 and TB-500 are both acidic: where does each chain’s charge come from?
From side chains, and in TB-500 from one end too. BPC-157’s lone lysine, at 7, faces three acidic residues, glutamate 2 and aspartates 10 and 11, while its free amine and free carboxyl cancel, so near neutral pH it sits at about -2. TB-500’s nine lysines face eleven glutamates or aspartates, and the acetyl cap leaves no amine at serine 1 to offset the carboxyl after serine 43, so it sits at about -3. Neither chain holds an arginine or a histidine.
Which is cheaper per mg, BPC-157 or TB-500?
Strength for strength, BPC-157 costs less per mg at the two strengths both sell by the single box: at 5mg $0.764 per mg against $1.428 (BC5, TB5), at 10mg $0.553 per mg against $1.034 (BC10, TB10).
What are the molecular weights of BPC-157 and TB-500?
BPC-157’s calculated average mass is 1,419.6 g/mol and TB-500’s 4,963.5 g/mol, 3,543.9 apart; in electrospray the ions come at m/z 1420.6 and 710.8 (1+ and 2+) for BPC-157 against 1655.5 and 1241.9 (3+ and 4+) for TB-500. On each certificate the measured mass is matched to the line’s calculated average mass, within about one unit, as how to read a peptide COA sets out.
Are BPC-157 and TB-500 made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, matched to the calculated figure on each sheet. The retest date is on the batch record. What differs is each molecule’s own chemistry, described on its compound page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.