Cagrilintide vs Semaglutide
Strength for strength, Semaglutide costs less per mg at the two strengths both are offered in: at 5mg $0.524 per mg against $1.820 (SM5, CGL5 in 50-box lots), at 10mg $0.384 per mg against $1.618 (SM10, CGL10 in 50-box lots). By the single box, Semaglutide is the only option, from $0.301 per mg at 30mg (SM30); every Cagrilintide line is special order. Cagrilintide is offered in 2 strengths (5mg to 10mg), Semaglutide in 7 (5mg to 50mg); Semaglutide has 2 on the shelf today, Cagrilintide none (special order, 50-box minimum). The least either takes: one box of SM5 at $26.20, four for a first order’s $100 minimum, against 50 boxes of CGL5, $4,550.00 of goods.
Prices revised · USD per box of ten · freight included to US addresses from $1,000 of goods · COA per batch · research use only · New to us? What can be checked before you pay
What differs between Cagrilintide and Semaglutide
Different families that are often ordered together: cagrilintide is a lipidated amylin analogue with a disulfide ring, semaglutide a lipidated GLP-1 analogue with none. They are also supplied co-formulated in three strengths, listed below the pair; the certificate identifies each component, and its purity is one figure for the vial.
| Detail | Cagrilintide | Semaglutide |
|---|---|---|
| Best per mg, by the box | Special order only | $0.301 per mg (SM30) |
| Best per mg, special order included | $1.618 per mg (CGL10, 50 boxes) | $0.283 per mg (SM50, 50 boxes) |
| Price per box sold singly | Special order only | $26.20 to $90.38 |
| In 50-box lots, per box | $91.00 to $161.80 | $50.90 to $141.28 |
| Strengths offered | 2: 5mg, 10mg | 7: 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg |
| Highest price per mg | $1.820 per mg (CGL5, 50 boxes) | $0.524 per mg (SM5) |
| On the shelf today | 0 of 2 strengths | 2 of 7 strengths |
| Range | GLP-1 & Metabolic | GLP-1 & Metabolic |
| Also called | NN0174-0833 | GLP-1 SG, GLP-1 Sema, NN9535 and NNC 0113-0217 |
| Form | Lyophilised powder | Lyophilised powder |
| Molecular weight | 4,409.1 g/mol | 4,113.6 g/mol |
| Formula | C194 |
C187 |
| CAS number | 1415456-99-3 | 910463-68-2 |
| Release limit | Purity ≥ 98.0 % by RP-HPLC | Purity ≥ 98.0 % by RP-HPLC |
Each line’s own page: Cagrilintide and Semaglutide. Reading either certificate: how to read a peptide COA. Checking a batch: verify a batch number. Every line priced: the price list. Checking another supplier’s quote: the price per mg calculator.
Strength for strength
Every strength both are offered in, per mg, the lower figure in bold; stock as this page was opened. Counting special-order lines, sold in 50-box lots, the lowest figures are $0.283 per mg for Semaglutide (50mg, SM50) and $1.618 per mg for Cagrilintide (10mg, CGL10).
| Strength | Cagrilintide | Semaglutide |
|---|---|---|
| 5mg | $1.820 per mg (CGL5, special order, 50 boxes) | $0.524 per mg (lower) (SM5, made to order) |
| 10mg | $1.618 per mg (CGL10, special order, 50 boxes) | $0.384 per mg (lower) (SM10, made to order) |
Every strength of both
Sold together
Cagrilintide 10mg + Semaglutide 10mg
Blend of Cagrilintide and Semaglutide
from $199.45 a box 1 strength
(special order)Cagrilintide 2.5mg + Semaglutide 2.5mg
Blend of Cagrilintide and Semaglutide
from $65.44 a box 1 strength
(special order)Cagrilintide 5mg + Semaglutide 5mg
Blend of Cagrilintide and Semaglutide
from $114.27 a box 1 strength
(special order)Compared elsewhere
Tirzepatide vs Semaglutide
At 30mg: $0.330 per mg against $0.301; 12 strengths against 7.
Semaglutide vs Liraglutide
At 30mg: $0.301 per mg against $0.523; 7 strengths against 3.
Retatrutide vs Semaglutide
At 30mg: $0.553 per mg against $0.301; 10 strengths against 7.
Questions
What is the difference between Cagrilintide and Semaglutide?
Different families that are often ordered together: cagrilintide is a lipidated amylin analogue with a disulfide ring, semaglutide a lipidated GLP-1 analogue with none.
Where does each carry its fatty diacid?
In different places. Cagrilintide carries its C20 diacid on a gamma-glutamyl unit bonded to the alpha-amine of lysine 1, the very start of the chain, with no polyethylene-glycol spacer, which leaves that lysine’s side-chain amine free. Semaglutide’s C18 diacid hangs from the side chain of lysine 26, reached through a gamma-glutamate followed by two mini-PEG units. They part at the other end too: cagrilintide closes in prolinamide, semaglutide in the free glycine acid of GLP-1 (7-37).
Which is cheaper per mg, Cagrilintide or Semaglutide?
Strength for strength, Semaglutide costs less per mg at the two strengths both are offered in: at 5mg $0.524 per mg against $1.820 (SM5, CGL5 in 50-box lots), at 10mg $0.384 per mg against $1.618 (SM10, CGL10 in 50-box lots).
What are the molecular weights of Cagrilintide and Semaglutide?
Cagrilintide’s calculated average mass is 4,409.1 g/mol and Semaglutide’s 4,113.6 g/mol, 295.5 apart; in electrospray the ions come at m/z 1470.7 and 1103.3 (3+ and 4+) for Cagrilintide against 1372.2 and 1029.4 (3+ and 4+) for Semaglutide. On each certificate the measured mass is matched to the line’s calculated average mass, within about one unit, as how to read a peptide COA sets out.
Are Cagrilintide and Semaglutide made to the same specification?
Yes: both are supplied to purity not less than 98.0 percent by RP-HPLC and net content within 5 percent of label, and each certificate reports those with a measured mass, matched to the calculated figure on each sheet. The retest date is on the batch record. What differs is each molecule’s own chemistry, described on its compound page.
Structural facts from each compound’s sheet and profile; prices and stock from the list at the moment this page was opened. How to compare strengths on price.