Thymosin Alpha-1 wholesale
Thymosin Alpha-1, also called thymalfasin. Bulk peptide powder in 10-vial kits, for sale in the USA and abroad: price and cost per mg
About Thymosin Alpha-1
N-acetylated 28-residue peptide, Ac-SDAAVDTSSE ITTKDLKEKK EVVEEAEN. 3 vial strengths, 2mg to 10mg, from $115.64 to $217.04 per box of ten, in US dollars (special-order lines from $50.90 a box at 50 boxes). 1 strength is on the shelf, leaving in 1 to 2 business days; the rest are made to order in about four weeks or special order, as marked.
Documents Specification sheet Verify a batch How to read the certificate What the purity figure means The mass result, explained
Thymosin Alpha-1 price per box, per vial and per mg
| Code | Strength | Per box | Per vial | Per mg | Stock | Order |
|---|---|---|---|---|---|---|
| TA2 | 2mg x 10 vials | $50.90 | $5.09 | $2.545 per mg | Special order, 50-box minimum | |
| TA5 | 5mg x 10 vials | $115.64 | $11.56 | $2.313 per mg | Made to order, 4 weeks | |
| TA10 | 10mg x 10 vials | $217.04 | $21.70 | Lowest $2.170 per mg | Low stock |
On the shelf, leaving in 1 to 2 business days: TA10. The others are made to order (about four weeks) or special order, as marked.
Ships from the USA: to US addresses at our risk until delivered (DAP), freight included from $1,000 of goods; to Canada and most other countries through the desk · on-shelf lines leave in 1 to 2 business days, then 1 to 3 business days in US transit · COA per batch · proforma in USD, paid by card, Wise, e-Transfer (Canada), Bitcoin or USDT · prices revised
Stock key
- In stock
- on the shelf, leaves in 1 to 2 business days once payment clears
- Low stock
- on the shelf and running low; leaves in 1 to 2 business days
- Ships in 1 week
- on its way in
- Ships in 2 weeks
- on order
- Made to order, 4 weeks
- made for the order, about four weeks
- Special order, 50-box minimum
- brought in on a 50-box minimum rather than held in stock; the desk confirms the date before you pay
Prices are in US dollars per sealed box. Per unit is the box price over the milligrams, millilitres or units in the box.
Thymosin Alpha-1 in brief
Thymosin Alpha-1 comes in 3 strengths from 2mg to 10mg per vial, each a sealed box of ten, from $115.64 to $217.04 a box for the strengths sold singly. Per mg the spread is narrow: TA10 (10mg x 10 vials) works out at $2.170 per mg against $2.313 per mg for TA5 (5mg x 10 vials), 6 percent less for the same mg, because the vial, the fill and the testing cost about the same whatever the vial holds.
One of the 3 strengths is on the shelf today (TA10) and leaves in 1 to 2 business days after payment clears; TA10 is running low. TA5 is made to order, about four weeks. TA2 is special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.
What Thymosin Alpha-1 is
Thymosin alpha-1 is a synthetic 28-residue peptide with an acetylated N-terminus, Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN, average mass 3108.3, corresponding to the N-terminal fragment of prothymosin alpha. It is a strongly acidic chain, with nine glutamates or aspartates against four lysines, and it has no methionine, cysteine, tryptophan or tyrosine.
With no oxidisable residue, oxidised forms are not the impurity to expect; what ages is the single asparagine at its C-terminus, by deamidation. It is very hydrophilic and has no tryptophan, tyrosine or phenylalanine, so it absorbs almost nothing above 220 nm; its peptide bonds absorb at 214 to 220 nm.
Registry and identity
- The international name for thymosin alpha-1 is thymalfasin, the INN from WHO Proposed INN List 77 and the USAN (code FF-51), filed by FDA's GSRS as UNII W0B22ISQ1C under CAS 62304-98-7, with DrugBank DB04900, ChEMBL CHEMBL2103979, MeSH C026455 and Merck Index m10830. FDA GSRS
- Prothymosin alpha, 111 residues in UniProt entry P06454 (gene PTMA), begins with these 28 after its initiator methionine, thymosin alpha-1 being positions 2 to 29, and GSRS records the first serine of thymalfasin as N-acetyl-L-serine. UniProt, FDA GSRS
- Worked from C129H215N33O55 (PubChem CID 16130571) with NIST isotope masses, the monoisotopic mass is 3106.504; a chain that had lost its N-acetyl group weighs 42.011 less, 3064.494, and its 3+ ion gives m/z 1022.505 against 1036.509. PubChem, NIST
A listing in these registers identifies a substance; it is not an approval of this line.
Thymosin Alpha-1 beside TB-500 and Thymalin
Thymosin Alpha-1 works out at $2.170 per mg at 10mg (TA10), its lowest by the single box. Its neighbours, on price alone: TB-500 at $1.034 per mg at 10mg (TB10), 4,963.5 g/mol, set side by side in Thymosin Alpha-1 vs TB-500; Thymalin at $0.925 per mg at 10mg (TY10, in 50-box lots), set side by side in Thymalin vs Thymosin Alpha-1.
Reading a Thymosin Alpha-1 certificate of analysis (COA)
Identity by mass. Average mass 3108.3 (C129H215N33O55). In electrospray the protonated ions come near m/z 3109.3 (singly charged), m/z 1555.2 (doubly charged), m/z 1037.1 (3x charged), m/z 778.1 (4x charged); on our certificates the measured mass is matched to the calculated average mass, within about one unit.
- Oxidation: no methionine, tryptophan or cysteine in the chain, so oxidised forms are not the impurity to expect.
- Deamidation: 1 asparagine. The deamidated form is 0.984 heavier and a little more negatively charged, inside the tolerance of the average-mass line; telling it apart takes a high-resolution mass, which the certificate does not carry.
- N-terminus: capped with an acetyl group, so there is no free N-terminal amine.
- Charge: near neutral pH about -6, acidic.
Worked out from what the sheet holds for this line; the batch certificate is the record. How to read one, and verify a batch number.
Buy Thymosin Alpha-1 in bulk
Thymosin Alpha-1 is sold in bulk by the sealed box of ten vials, and every account starts at list price. Two discounts can lower it, the size of one order (from $5,000 of goods) or the account’s tier (from lifetime paid spend), and the better one applies, never both. Priced below on TA10, 10mg x 10 vials, the best-priced strength.
| Discount | Earned by | Off goods | TA10 per box | Per mg |
|---|---|---|---|---|
| List | Every account, any order | none | $217.04 | $2.170 |
| Order size | $5,000 of goods in one order | 5% | $206.19 | $2.062 |
| Order size | $10,000 of goods in one order | 10% | $195.34 | $1.953 |
| Order size | $20,000 of goods in one order | 15% | $184.48 | $1.845 |
| Order size | $50,000 of goods in one order | 20% | $173.63 | $1.736 |
| Silver tier | $5,000 lifetime paid spend | 3% | $210.53 | $2.105 |
| Gold tier | $15,000 lifetime paid spend | 6% | $204.02 | $2.040 |
| Platinum tier | $50,000 lifetime paid spend | 10% | $195.34 | $1.953 |
| Diamond tier | $100,000 lifetime paid spend | 15% | $184.48 | $1.845 |
Thresholds in USD on goods, before freight; the discount is worked out at checkout and shown on the proforma.
Specification
The limits this compound is supplied to.
| Purity | ≥ 98.0 % (RP-HPLC, 220 nm, area normalisation) |
|---|---|
| Identity | ESI-MS against a calculated average mass of 3108.3 |
| Any single related substance | ≤ 1.0 % |
| Water | ≤ 8.0 % (Karl Fischer) |
| Acetate | ≤ 15.0 % (ion chromatography), as the acetate salt |
| Residual solvents | Acetonitrile ≤ 410 ppm; TFA ≤ 1.0 % |
| Net content | Label claim ± 5 % |
| Closure | 2 mL glass vial, bromobutyl stopper, aluminium flip-off seal |
| Storage | −20 °C, dark and dry; brief ambient transit tolerated |
| Shelf life | 24 months from manufacture; retest date on the batch record |
Order Thymosin Alpha-1
One box of TA10, 10mg x 10 vials, $217.04 a box. Every strength.
Questions about Thymosin Alpha-1
Is thymalfasin the same as Thymosin Alpha-1?
Yes. Thymalfasin and Thymosin Alpha-1 are names for the same thing. Thymalfasin is the international non-proprietary name of thymosin alpha-1, the N-acetylated 28-residue peptide sold as Thymosin Alpha-1. The certificate and the vial label carry Thymosin Alpha-1, which is the name the batch is released under.
What are Thymosin Alpha-1’s sequence, formula, molecular weight and CAS number?
Ac-SDAAVDTSSE ITTKDLKEKK EVVEEAEN, 28 residues with an acetylated N-terminal serine: C129H215N33O55, molecular weight (average mass) 3,108.3, CAS 62304-98-7, which FDA’s GSRS files as UNII W0B22ISQ1C under the international name thymalfasin.
How much does Thymosin Alpha-1 cost?
From $115.64 a sealed box of 10 vials, up to $217.04 for the largest strength sold singly, which works out at $2.170 per mg at its best-priced size. TA5, the cheapest box sold singly, is made to order, about four weeks; the cheapest on the shelf is TA10 at $217.04. TA2 is special order, 50 boxes at least, at $50.90 a box. To a US address, freight is included from $1,000 of goods; below that it is the carrier’s rate for the carton or a flat $35.00, and to another country the desk quotes it; either way the figure is on the proforma before you pay. Every strength and its price per vial is in this page’s price table.
Which Thymosin Alpha-1 size is cheapest per mg?
TA10, 10mg x 10 vials, at $2.170 per mg, which is 6 percent less per mg than TA5, at $2.313 per mg. Larger vials cost less per mg across this range, so match the vial to the size of the work first, then compare per mg.
Can I buy a single vial of Thymosin Alpha-1?
No. One sealed box of ten vials is the smallest quantity of a regular line; for Thymosin Alpha-1 that is TA5, 5mg x 10 vials, at $115.64. A first order must reach $100 of goods, which one box of TA5 clears. TA2 is special order and takes a minimum of 50 boxes. A box is sealed at fill with its batch number on it, and splitting one would break the link between the vials and their certificate.
Which Thymosin Alpha-1 strengths are in stock today?
TA10 at $217.04 a box (running low). TA5 is made to order, about four weeks. TA2 is special order: brought in on a 50-box minimum rather than held in stock; ask the desk for the date before ordering.
How is Thymosin Alpha-1 stored?
At minus 20 degrees Celsius, dark and dry. Lyophilised powder tolerates a short spell at ambient temperature in transit, which is why boxes ship without ice. Storage and handling.
What is in a box of Thymosin Alpha-1?
Ten sealed vials of one strength, each labelled with the product code, the strength and the batch number; the trade also calls a box a 10-vial kit. Thymosin Alpha-1 is supplied as a powder in a sealed glass vial and in no other presentation. Boxes are not split.
Is a certificate of analysis (COA) provided for Thymosin Alpha-1?
Yes. For Thymosin Alpha-1 the batch certificate reports its purity, net content and identity by mass spectrometry. The other lines on this page are the specification it is made to, and the desk answers for them on a particular batch. The certificate is sent with the shipment, and again on request, and any batch number can be verified on the certificate page.
Is this for human use?
No. Everything here is supplied for laboratory research only, to trade accounts, and is not for human or animal consumption. The research-use page sets out who can buy and what is not sold.